Sentence examples for many pathophysiological states from inspiring English sources

Melatonin (Mel) has been successfully used as a potent antioxidant against many pathophysiological states.

These findings have wide-ranging implications for the many pathophysiological states in which MIF plays an important regulatory role and suggest a potential therapeutic role for MIF in modulating clinical conditions associated with age-related decline in estrogen levels.

OPN is over-expressed in many pathophysiological states associated with insulin resistance and type 2 diabetes, such as, in the aorta of hyperglycemic diabetics, atherosclerotic lesions, activated macrophages, steatotic hepatitis, end-stage kidney failure, and osteoporosis.

This approach has demonstrated a role for both transcriptional and translational regulation in many pathophysiological states such as drug resistance and cell-cycle control [ 6, 7].

The RTI method has been used extensively by the Nicholson laboratory in New York with emphasis on the normal brain and by Eva Syková and colleagues in Prague, where many pathophysiological states have been investigated (for a comprehensive review see Syková and Nicholson [ 20]).

Lysophospholid signaling systems such as LPA and sphingosine-1-phosphate have been associated with many physiological and pathophysiological states, including cell differentiation, smooth muscle contraction, cancer, multiple sclerosis, cardiovascular disease, and asthma.

Shubin and Weil [ 19] defined the pathophysiological states of circulatory shock many years ago, using a classification based on four mechanisms (Table 1, Figure 4).

Three pathophysiological states have been described for cardiogenic shock (Fig. 1): Fig. 1 Cardiogenic shock Warner Stevenson concept (2).

Exosomes, nanosized EVs of endosomal origin, regulate many pathophysiological processes including immune responses and inflammation, tumour growth, and infection.

Up-regulation of ligand and receptor is also associated with pathophysiological states such as cardiac dysfunction and neovascularisation.

In the following review, a description of cellular redox regulation under normal and pathophysiological states will be presented.