Sentence examples for several pathophysiological states from inspiring English sources

The structure of the synthesized inhibitors was designed to target human neutrophil elastase, a serine protease whose uncontrolled activity may lead to development of several pathophysiological states such as rheumatoid arthritis, cystic fibrosis or tumor growth and invasion.

Pituitary adenylate cyclase-activating polypeptide (PACAP) is a 38- or 27-amino acid neuropeptide with promising therapeutic applications for the treatment of several pathophysiological states related to neurodegenerative diseases.

Finally, given the relevance of TNF in several pathophysiological states such as cancer and aging [51], [52], and its connection with the deregulation of the Notch signaling pathway implicated in these diseases [26], [53], [54], suggests that the significance of TNF regulation of Notch-1 may extend to tissues other than skeletal muscle.

These findings strongly suggest that MIF is involved in various pathophysiological states beyond the immune system.

A large number of potential biomarkers for NPC related to various pathophysiological states have been identified.

Furthermore, PXR action in various pathophysiological states indicates that PXR agonists could variably affect human and animal health.

A large number of potential biomarkers for this disease related to various pathophysiological states have been discussed.

A deregulation of the hypothalamic NPY system has been proposed to be related to several pathological and pathophysiological states including cancer cachexia [ 99], hyperinsulinemia and hypercorticism [ 100], obesity and metabolic syndrome [ 101], and anorexia [ 102].

These two disorders share several pathophysiological mechanisms.

Several pathophysiological mechanisms of action have been proposed.

Several pathophysiological mechanisms that might limit further recovery in MCS patients are considered.