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Calpains are calcium-dependent proteases with many cellular targets including cytoskeletal elements.
A product of the ob gene, 3 leptin has many cellular targets in different organs.
In accordance with the multiple properties and clinical effects ascribed to curcumin, many cellular targets have also been proposed.
We suspect that MEKK1 is one of several or many cellular targets that contribute to the multiple effects of ITCs.
Activation of signaling cascades in response to stress, growth factors or immune stimulation ultimately results in the phosphorylation of many cellular targets including histone proteins.
It was reported that curcumin could interact with many cellular targets such as nuclear factor-kappa B (NF- κB) and transcription factor activator protein-1 (AP-1) [ 22– 22].
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In addition, many cellular targeting signals are located within UTRs [ 37].
Many putative cellular targets are affected by sulforaphane although only one, KEAP1-NRF2 signaling, can be considered a validated target at this time.
The anti-cancer mechanism of quinacrine is complex, with many potential cellular targets.
Hence, we expect that many additional cellular targets of insulin will emanate from studies of this kind.
Fibroblast growth factor (FGF 2 is a ubiquitously expressed pleiotropic growth factor with many recognised cellular targets and tissue effects.
Related(20)
multiple cellular targets
many molecular targets
diverse cellular targets
several cellular targets
many cellular activities
many cellular responses
many cellular pathways
many ambitious targets
many cellular events
many potential targets
many cellular components
many cellular proteins
many cellular substrates
many cellular processes
many such targets
many cellular factors
many cellular enzymes
many many targets
many cellular transformations
many important targets
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