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Among the many cellular activities reported to be subject to mechanical regulation are the expression and activation of MMPs in vivo and in vitro [ 21].
Nucleophosmin, a multifunctional nucleolar phosphoprotein, is involved in many cellular activities.
Microtubule dynamics are critical for many cellular activities, such as cell division, cell migration, and cell polarization.
The presence of histamine could influence the acid base balance or the pH levels of many cellular activities (e.g., gastric or mucus secretion, exocytosis, Ca+2 fluxes) or ionic composition of surface proteins that would lead to minor or major alterations in the integrity of intra-, extra-cellular or vascular components and the endothelial barrier function.
Caffeine, which elicits well-documented cytotoxic effects to eukaryotic cells, has been proposed to target and inactivate many cellular activities (Fig. 7).
Among the many cellular activities in which proteases are involved, proteolysis is known to be essential for the maturation of several microneme proteins [37], [40], [53], [63] [65].
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The importance of stochasticity of gene expression in many key cellular activities was appreciated many decades ago, and is now supported by strong experimental evidence [ 11].
Reactive oxygen species (ROS) are free radicals naturally produced in the cells and are involved in many cellular biochemical activities such as signal transduction, gene transcription and regulation of soluble guanylate cyclase activity [ 6, 7].
The GAPDH activity may influence many other cellular activities, facilitating a greater capacity for adaptation to environmental challenges or growth conditions.
The nuclear factor NFκB is a well-studied and widely known transcription factor, which is involved in the regulation of many important cellular activities.
In plants, both carbon (C) and nitrogen (N) are crucial for many fundamental cellular activities, and are required not only as nutrients but also as environmental signals to control metabolism and cellular responses [ 21].
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many other activities
many biological activities
many cellular functions
many cellular events
many cellular pathways
many cellular effectors
many cellular components
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many cellular phones
many cellular proteins
many cellular substrates
many cellular processes
many cellular factors
many cellular enzymes
many cellular transformations
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