Sentence examples for mutations is needed from inspiring English sources

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A comprehensive approach to the study of TAAs resulting from genetic mutations is needed to translate this information into advances in treatment.

A rapid genotyping test with high accuracy, selectivity, and reproducibility suitable for the determination of known mutations is needed for prenatal screening and post-natal diagnosis of this disease in clinical setting.

More analysis, including protease inhibitors resistance mutations, is needed to fully understand the underlying mechanisms of reversion of multi-drug resistant HIV in the absence of drug pressure.

A full reconstruction of this complex landscape of adaptive mutations is needed for elucidation of biological mechanisms of viral adaptations to humans.

Thus, knowledge about detection of these mutations is needed.

To uncover the neurobiological significance of these variants, investigation of the functional effects of the putative mutations is needed.

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Interestingly, at least 500 mutational catalogs with an average of 96 mutations per catalog (a total of ∼50,000 mutations) are needed to decipher five mutational processes, but these five mutational processes can be more easily deciphered from 50 cancer genomes containing an average of 480 mutations (a total of ∼25,000 mutations, Figure 3D).

Taken together present finding clearly indicate that alterations in DDR genes are relevant for development of canine cancer, however to shed more light on tumor-associated defects, further investigations of different canine tumor types with regard to their mutational status and in particular the functional effects of mutations are needed.

A few years ago, researchers thought that about five to seven mutations were needed to trigger the uncontrolled cellular proliferation that defines the disease.

Other research has indicated that genetic vulnerability to autism differs between males and females, with more mutations being needed to produce the condition in females compared with males.

In "Cancer's Genome" Emily Singer, Technology Review's biomedicine editor, describes how research has proved that cancer genomics are "even more complicated than scientists had supposed". We now understand that five to as many as 20 mutations are needed to trigger cancer's cellular proliferation.

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