Sentence examples for mutations and modifications from inspiring English sources

Thus, natural mutations and modifications of the coding region of Hd6 within the genus Oryza have been suppressed during its evolution; this is supported by low Ka (≤0.003) and Ka/Ks (≤0.576) values between species, indicating purifying selection for a protein-coding gene.

Moreover, Arf mutations and modifications are associated with decreased survival in patients with OS [20].

Factors that influence its processing via CMA including various α-synuclein mutations and modifications including oxidative damage and S129 phosphorylation can lead to α-synuclein accumulation.

But different tRNA isoacceptors may be altered in their reading capacity through mutations and modifications of their first anticodon bases, i.e. changed in which wobble rule they use.

The detection of insoluble SOD1 in ALS patients suggests that mutations and modifications could lead to conformational changes in SOD1 that, in turn, increase the chances that it will misfold and form insoluble aggregates (Bosco et al., 2010).

The fact that other patients with BMP4 deletions/mutations do not demonstrate the full SHORT syndrome phenotype may be explained by variable phenotypic expressivity of BMP4 mutations and modification of their effect(s) by other genetic factors located elsewhere in genome.

The chromosomes will be passed to the next generation through a four-step breeding process including Selection, Crossover, Mutation, and Modification.

These data indicate that little natural mutation and modification in the TAC1 coding region occurred within the cultivated rice and its progenitor during evolution.

In our Drosophila model, relative impacts of TDP-43 mutation and modification on TDP-43WT-mediated neural deficiency ranged from mild (A315T) to drastic (N390D; FFLL).

We have discussed genomic mutations and epigenetic modifications in pediatric asthma and ASD.

In this case, mutations and chemical modifications at one position of the RNA can be considered as the interaction of a ligand.