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To test the contribution of PPK2 to C. jejuni host colonization, we tested the ability of the Δppk2 mutant to colonize day-old chicks.
Colonization analysis also revealed the incapability of the ΔsalKR mutant to colonize any susceptible tissue of piglets when administered alone.
These data indicated that overproducing DbpA alone fully restores the ability of the mutant to colonize the heart, joint and skin tissues.
Complementation of the ΔSPI-19 mutant strain in trans, restored the ability of this mutant to colonize the gut and internal organs of infected chickens.
The ability of the MAH 4B2/ΔGPL mutant to colonize the C. elegans intestinal epithelium is lower compared to the wild-type MAH infection as indicated by a significant decrease in the amount of bacteria localized in the intestine after pulse-chase analysis.
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According to the story presented in the game's manual, the overpopulation of Earth in the early 21st century has caused the international government to exile certain members of the human race, such as criminals, the cybernetically enhanced and genetic mutants to colonize the far reaches of the galaxy.
We also carried out the nasopharyngeal colonization and pneumonia infections in the absence of competition to assess the ability of the mutants to colonize and to produce pneumonia in the absence of competition from the susceptible parent.
We next investigated the ability of these mutants to colonize tissues of the GI tract by analysing fungal burdens at various sites on day 10 post infection (Fig. 1C).
In our experiments, transfer of the complete SPI-19 region into the ΔSPI-19 mutant strain restored the ability of the mutant isolate to colonize ileum, ceca, liver and spleen directly linking SPI-19 to the colonization defect in our ΔSPI-19 mutant (Figure 5).
Indeed, in a screen that identified K. pneumoniae mutants failing to colonize mice [ 39], two of them were mutants in genes coding for proteins annotated as hypothetical, that have been subsequently re-annotated as T6SS proteins [ 38].
Drastic differences were observed in the capacity of the B128 WT and the ΔcagY-mutant strain to colonize the gastric antrum and corpus mucosa inducing severe inflammation over time.
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variant to colonize
line to colonize
mutant to promote
mutant to create
mutant to complement
mutant to represent
mutant to dissect
mutant to identify
mutant to impair
mutant to vaccinate
mutant to accumulate
mutant to go
mutant to mediate
mutant to limit
mutant to H3K4me3
mutant to form
mutant to observe
mutant to synthesize
mutant to transform
mutant to transport
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Justyna Jupowicz-Kozak
CEO of Professional Science Editing for Scientists @ prosciediting.com