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One may have expected the above KaiCTSa mutant to represent the state before dephosphorylation of the second P-site (pS431).
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The THIC gene of Arabidopsis, recently found to play an important role in thiamine biosynthesis [44], [45], appears based on map location and distinctive mutant phenotype to represent the classical PY locus, first described by Feenstra [46] and Rédei [47] more than 40 years ago.
The fourth phenotypic class, approximately 1/16 of the total number of embryos, exhibited defects resembling both trpm7 and enz mutant embryos, and is presumed to represent double mutants.
The PID LF mutant has been thought to represent a functionless, inert control for the PID, incapable of inhibiting Pak or binding to its partners such as the Fragile X protein [41].
Since A is a constant that applies to all mutants in the pool, the relative growth rates of the mutants can be used to represent the FCC of the corresponding gene with the reduced copy number.
The fuzzy equivalence relation based on a phase space is employed to represent the mutant gene and the optimum measure for fuzzy equivalence relation is advanced to uncover the essence of variation of the rolling bearing performance.
Positive (mutant) samples should be chosen to represent as broad a range of results as possible, bearing in mind the desire or requirement for extrapolation of the results.
However, its expression is lost during the evolution from adenoma to carcinoma, whereas p53 expression is increased, an event generally coincident with the expression of stabilised p53, which we presume to represent the mutant form.
Characterization of these 18 mutants revealed that they appear to represent nine independent mutagenic events.
If the three mutant babies represent mankind's generations to come, one would have to conclude that Cai's vision of our environmental future is dark indeed.
To test whether retained WRN phosphorylation mutant foci represent non-repaired DSBs, we performed alkaline comet assays.
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