Sentence examples for murine models such from inspiring English sources

This concept was immediately extrapolated to human disorders that are considered equivalent to the above-mentioned murine models, such as multiple sclerosis, rheumatoid arthritis and inflammatory bowel disorders [ 55], but also to psoriasis, contact dermatitis and atopic dermatitis [ 56].

Athymic nude mice are preferable to other immunocompromised murine models, such as SCID or NOD-SCID mice that have coexisting abnormalities of DNA repair, which are likely to influence normal tissue toxicity (Chang et al, 1993).

EP also protects against liver injury in a couple of murine models such as acute alcoholic hepatitis [ 21], hemorrhagic shock [ 22], sepsis [ 23], acute extrahepatic obstruction [ 24], and acute necrotizing pancreatitis [ 25].

Supporting this assumption, the observation of impaired autophagy in our model is similar to those obtained in some LMNA-related murine models: such as Lmna knockout mice (dilated cardiomyopathy and muscle dystrophy) and Zmpste24-deficient mice (extreme phenotype of premature aging) [ 50, 51].

Although many differences exist between our colitis model induced by a lymphopenic driver, other murine models, such as dextran sodium sulfate-induced acute colitis model, and human IBD, we propose a pathological role of IL-7-producing MSC at least in our model.

Previous reports showed that growth of human tumours could be recapitulated in non-murine models such as the zebrafish.

For such a demonstration in murine models, procedures such as gonadectomy and reverse hormone replacement have been crucial [12], [64], [65].

Our group has recently demonstrated that infection with T. crassiceps reduces the incidence and severity to T1D [ 11], EAE [ 12], and colitis (unpublished observations) in murine models, and such protection has been associated with immunoregulatory mechanisms induced by this parasite.

An influence of estrogen status on the development of SLE is clearly demonstrated in murine SLE models, such as the (NZB × NZW F1 mouse.

In contrast, certain in vivo murine MM models such as the 5TMM model [ 19] or transgenic mouse models [ 20] have been successfully exploited for studying MM-immune cell interaction and immunotherapy [ 21, 22].

Lactulose was reported to modify systemic immune responses in a murine model; however, such findings were not confirmed by our immunoglobulin measurements.