Sentence examples for multiple mutations the from inspiring English sources

To make strains carrying multiple mutations, the tet resistance marker was removed by growing them on Maloy Nunn medium [ 43].

For those that contained multiple mutations, the individual mutations could all contribute in an additive manner or some of these mutations could be silent or partially deleterious.

Furthermore, Klampfl et al. showed that in two PMF patients with multiple mutations, the CALR mutations were early events, that is, they had already been present in the proliferative phase of PMF.

A previous study [ 7] demonstrated that in the case of single or multiple mutations, the specificity of the wild type is not lost, but there is an increase in new substrate specificity.

The next step was based on the observation that as long as differences in fitness arise from the accumulation of multiple mutations, the branching structure of this family tree will bear a visible imprint of the natural selection process as it unfolds.

Meanwhile, a delicate study demonstrated that the aroma production in fragrant genotypes was well correlated with the multiple mutations in the fragrance rice (fgr) locus that is identical to betaine aldehyde dehydrogenase (OsBADH2) on chromosome 8 [ 22].

Random NTG mutagenesis can result in the introduction of multiple mutations into the genome of each strain, complicating the identification of the specific mutations that are relevant to the molecular target.

However, given the observed divergence between these two species (Escalante et al. 2005; Pacheco et al. 2012b), we corrected by the possibility of multiple mutations in the same site by using the Jukes Cantor model.

Lung cancer might also be linked to the loss of genes or genetic mutations that occur in the 1p36.2 region (FRAP1), the 6p25.2-q27 region (PARK2), or multiple mutations in the 10q region and the 11q13 region (CCND1).

As found for K227Q, reactions containing the ligases with multiple mutations, showed the majority of P signal co-migrating with the adenylated adapter.

Unless it is necessary to preserve multiple mutations or the entire genome, the efficiencies reported here make sperm cryopreservation preferable to embryo cryopreservation in many cases, provided appropriate females will be available in the future.