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Exact(5)
Hence their multiple forms may be attributed to their multiple cellular locations [ 39].
In conclusion, TORC2 appears to be at multiple cellular locations, the plasma membrane, and one or possibly more other sites.
HSPA5 belongs to the family of 70-kDa heat shock proteins generally found in the endoplasmic reticulum; however, it is associated with multiple cellular locations and functions, including the unfolded protein response, protein transport, and interactions with apoptotic executors [ 63].
Other RGG-box proteins are known to have multiple cellular locations, for example, nucleolin and the Ewing Sarcoma (EWS) protein (#26, Table S1) are found on the cell surface as well as in the nucleus and cytoplasm.
While this has led to the use of FluoZin-3 for monitoring multiple Zn2+ pools, it can lead to complications because the probe may report on Zn2+ within multiple cellular locations.
Similar(55)
As the probes are not localised to any intracellular domains [41], the readout reflects changes in "global" cAMP concentrations and this is appropriate as we show that moexipril has activity against multiple PDE4 isoforms (Fig. 3) that are known to target, via unique N-terminal sequences, multiple and distinct cellular locations [9,10].
Alternatively, YATA and its related proteins might have multiple cellular functions at several subcellular locations.
A protein is often represented in multiple post-translational states, complexes, or cellular locations.
NS1 exists in multiple oligomeric forms and is found in different cellular locations: a cell membrane-bound form in association with virus-induced intracellular vesicular compartments, on the cell surface and as a soluble secreted hexameric lipoparticle.
Once at the intended cellular locations, the effectors participate in multiple cellular functions such as signaling, nuclear processes, endocytosis, cytoskeletal remodelling, cell survival, membrane trafficking, phagosome maturation and autophagy [ 4- 6].
In other words, even though the "lock and key" idea of chemical binding is long past its prime, it is tempting to imagine that multiple molecular keys on a NP surface might open multiple cellular locks in a coordinated way if the spatial locations were well-matched.
Related(20)
various cellular locations
multiple cellular changes
multiple cellular functions
multiple cellular events
multiple cellular origins
multiple cellular steps
multiple cellular processes
multiple cellular roles
multiple cellular subsets
multiple cellular sensors
multiple cellular parameters
multiple cellular compartments
multiple cellular pathways
multiple cellular conditions
multiple cellular proteins
multiple cellular sites
multiple metastatic locations
multiple cellular levels
multiple cellular targets
multiple cellular effects
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