Sentence examples for mouse models develop from inspiring English sources

These two mouse models develop neuropathological hallmarks of AD differently in young adulthood.

Both mouse models develop medulloblastic tumors spontaneously between 2 and 10 months of life.

Both of these mouse models develop autoimmunity with elevated antibody titers against immunoglobulin (Ig) G and type II collagen.

Both mouse models develop ER-negative mammary tumours, suggesting that the well-tolerated rexinoid is an effective agent for the prevention of ER-negative breast cancer.

Although most of the mouse models develop typical amyloid plaques and cognitive deficits with age, the pathophysiology in young transgenic mice, reflecting preclinical forms of AD, is less well understood [ 63].

All of these mouse models develop some features of CS, although there are some notable differences; however, the effects of endogenous glucocorticoid excess on bone have only recently been reported in the CRH-overexpressing transgenic model (16).

Mouse models developed more recently have implicated LGI1 in neuronal maturation processes.

This inhibitory effect of the non-specific effectors on intra-hepatic Plasmodium parasites is not surprising, such "cross-pathogen" defense mechanisms have been described in transgenic mouse models developed by the group of Chisari [5], [47].

Mouse models developed thus far have provided researchers with new insights into the molecular mechanisms and pathways involved in bladder cancer.

Intriguing insights have been gleaned from new mouse models – developed to circumvent the embryonic lethality of SIRT1 knockout (KO) mice – that either lack or overexpress SIRT1 in a tissue-specific and/or inducible manner.

Here we will review the most relevant genetic mouse models developed by targeted inactivation of ASD-associated genes, and discuss their importance for the development of novel pharmacological therapies of these disorders.