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Mouse models corroborate these findings.
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Evidence from mouse models corroborates data obtained from human studies.
Studies in mouse and ferret models corroborate the finding that previous infection with influenza virus can render a host more susceptible to secondary bacterial infection (Peltola et al., 2006).
Several theories and models corroborate the multidimensional construct of work-related FC [ 7, 8].
The link between Wnt signaling and the PU.1-kd-driven AML mouse model is corroborated by earlier observations that PU.1 is targeted by Wnt pathway members [ 21].
Studies in genetic mouse models have further corroborated the metabolic benefits of browning.
Studies in mouse models of OA corroborated the association between cartilage degradation and an overactivation of Wnt signaling.
Altogether, these results corroborate our observations in mouse models and validate the strong correlation between the loss of miR-203 and the development of skin cancer at multiple stages of tumorigenesis.
In addition, our results in a mouse model of lupus corroborated by recent studies in human SLE, indicate that miR-21 plays a central role in regulating autoimmune responses in lupus and that miR-21 inhibition can favourably alter the course of a systemic autoimmune process, opening new directions for explorations of miRNA therapeutics in SLE.
In summary, the in vivo selectivity of ELN475516 from a mouse seven-day safety model corroborates the improved selectivity estimated for this compound in the cellular SNC assay, confirming APP selective inhibition of gamma-secretase in vivo by this novel pyrazolylazabicyclo(3.3.1 nonane sulfonamide.
Blocking E-cadherin causes selective disorganization of the luminal cells; this relationship between tissue structure and developmental morphogenesis has been corroborated in mouse models (for review [ 10]).
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