Sentence examples for mouse crypts develop from inspiring English sources
Mouse crypts develop postnatally and are the architectural unit of the stem cell niche, yet the pathways that drive their formation are not known.
Xenografted organoids formed crypt structures distinctively different from surrounding mouse crypts, reflecting their human origin.
These mice spontaneously develop aberrant crypt foci and have increased susceptibility to dextran sulfate sodium-induced colitis [37].
Predictions of this theory were tested using mouse crypt regeneration and mouse skin as biological models.
Furthermore, 19% of all heterozygous and 37% of all homozygous gpA33ΔN-Bcat mice spontaneously developed aberrant crypt foci and adenomatous polyps, at frequencies and latencies akin to those observed in sporadic colon cancer in humans.
Indeed, double GPX1/2 knockout mice develop spontaneous colitis, which is characterized by infiltration of neutrophils and formation of crypt abscesses, (Esworthy et al., 2001; 2003,), consistent with the pathological features of S. Typhimurium-induced enteritis.
Supplementary Figure 6 Pik3cdE1020K/+ mice develop IgM autoantibodies.
Conditional inactivation of HNF4α gene in the colon in mice resulted in a failure to develop crypts, and a series of intestinal expressed genes were affected by the lack of HNF4α expression [ 27].
On the face of it, the mouse developed normally.
All but one unimmunized mouse developed tumours.
Cyclophilin C-associated protein (CyCAP -/- miCyCAP -/-aneously developed colonic micespontaneouslyia early in life comparedeveloped-type micolonic (p < 0.0001, T-test) and crypts of colonic mucosalof thyperplasia/- micearlyw hinher proliferation rate (p = 0.039, Mann-Whitney Test) and larger number of compared1-positove cells (p < 0.0001, Mann-Whitney Test).
