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First, DNA methylation was a modulator of gene transcription.
The TiO2NPs were more potent modulator of gene expression in the brain than AgNPs, despite the two times lower dosage.
Genome-wide microarray and gene ontology analyses of treated endothelial cells revealed derivative 18c as the most efficient modulator of gene expression and "mitotic cell cycle/cell division" along with "cholesterol biosynthesis" as the most significantly altered biological processes.
Other studies have already shown that Al is a potent modulator of gene expression at both high and low concentrations [12][13], [14].
The expression changes of these genes were only a few folds, a finding consistent with the fact that Sox6 does not have a transactivation or transrepression domain, and has been shown to act in other cell types as a positive or negative modulator of gene expression [23].
A number of studies have suggested that PRKDC acts as a modulator of gene transcription.
Similar(43)
Anderson, P. & Kedersha, N. RNA granules: post-transcriptional and epigenetic modulators of gene expression.
Regulatory RNAs are increasingly recognized and utilized as key modulators of gene expression in diverse organisms.
These methods will facilitate investigations of whether miRNAs interact with sequences outside of 3′-untranslated regions and suggest new targets for the design of synthetic modulators of gene expression.
MicroRNAs (miRNAs) have recently been discovered to be regulatory modulators of gene expression [6].
Hormones and vitamins are key modulators of gene expression that should be considered.
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