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Exact(6)
The degree of CNT-bacteria aggregation was influenced by CNT functionalization and length may modulate the toxic effect on the bacteria.
We used representative skin cell lines and in vitro assays to assess whether the cationic compounds modulate the toxic responses of these nanocarriers.
Post-translational modifications modulate the toxic properties of proteins involved in human neurodegenerative diseases and, for this reason, could be targeted for therapeutic intervention.
To accomplish these objectives, one must consider the main factors which may influence and modulate the toxic effects of chemicals in the organ.
We have also identified genetic effects on Cu, Se, and Zn, which are not among the toxic elements but are essential and may modulate the toxic effects of the other elements.
In addition, both pathways have been shown to modulate the toxic effects of amyloid-β oligomers on NMDA receptor-dependent synaptic transmission, and to control common intracellular effector molecules, including Src family kinases, the Rho GTPase Cdc42 or the actin-binding protein cofilin.
Similar(54)
Although this conformational variation is still undetermined in polyQ diseases, specific amyloid conformations adopted by each protein containing polyQ segments can affect different cellular factors including proteins, thereby modulating the toxic effects.
The unique profile of tolerability and antitumour activity of IDN 5390 is likely related to still unrecognised changes in drug cellular interactions that may be critical in modulating the toxic and therapeutic effects of taxanes.
As these four modifiers could modulate both the toxic effect of this transgene and the toxic effect of a non-coding CAG-repeat RNA, we were interested in whether the mitigation of the Ataxin-3 toxicity was due to a selective effect on the RNA versus an effect on both the protein and the RNA.
We chose to study the toxic species of ataxin-1 that expresses an expanded polyQ repeat as our aim was to modulate the toxicity of this species using protein domains distal to the repeat.
Administration of TQ significantly improved the negative effects of some of the hepatic biomarkers and modulated the other toxic effects.
Related(20)
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modulate the ionospheric
modulate the electronic
modulate the endogenous
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modulate the atmospheric
modulate the swCNT
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