Sentence examples for modulate the deleterious from inspiring English sources

The budding yeast offers a convenient system to monitor amyloid toxicity [5] [7] and has allowed in the past pinpointing genes that modulate the deleterious consequences in other eukaryotic models [8].

Therefore, augmentation of angiogenesis in the CColder group may be a compensatory process to modulate the deleterious impact of hypoxia.

Identification of novel mechanoresponsive proteins such as YAP and TAZ will provide new therapeutic targets to modulate the deleterious effects of increased mechanical force.

The role of HGF in teleost is largely unknown, and in this case its activation may be an attempt to counterbalance the loss of cell population or to modulate the deleterious effects of an exacerbated immune response.

Transforming growth factor-beta, alendronate, and raloxifene analog may have potential in modulating the deleterious bone effects of CsA [ 7, 12, 13].

Diploid individuals benefit from heterozygosity to modulate the effects of damage or deleterious mutations as well as from increasing diversity through the recombination events between the parental chromosomes.

These two substances enabled us to modulate the severity of the inflammatory stimulus, especially regarding the deleterious effects on CHDR.

Accordingly, administering an anti-inflammatory flavonoid named quercetin [ 125] during pregnancy and lactation significantly decreases ER stress activation in the offspring [ 126], suggesting that it may be possible to modulate the prenatal environment, preventing ER stress and its deleterious consequences.

Moreover, if we can identify potentially deleterious genetic polymorphisms, then we will be able to modulate the expression of the involved genes using specific gene therapies.

The mechanism that makes NO production deleterious to cells seems to be related to protein nitrosylation and nitration, which can modulate the function of various enzymes and ion channels as well as different signalling pathways [ 23].

As soluble oligomers are believed to modulate the mechanism of PD pathogenesis mainly by formation of pores in neuronal membranes, resulting in leaching of vital components of the cytoplasm with deleterious effects for the cell, our results provide a mechanistic rationale for the observed beneficial role of nicotine on the progression of the disease.