The composition of the mixed solvents and the volume ratio of ethanol modulated the primary particle size of the Li4Ti5O12 nanoparticles.
Amlodipine-induced regression of aortic hypertophy and aortic SMC hyperplasia were dose- and time-dependent, but there was no interaction between atorvastatin and amlodipine in modulating the primary endpoints.
For example, miR-126 inhibits breast cancer metastasis either by modulating the primary tumor microenvironment (Zhang et al., 2013) or by inhibiting lung metastatic colonization (Png et al., 2012) in mouse or human breast cancer models, respectively.
C5a did not modulate the activation of primary cultures of HSC, nor increase Col1A1 expression.
VDR polymorphisms have been investigated with regard to their potential to modulate the susceptibility for primary biliary cirrhosis.
In any case, a surprise effect in early visual cortex accords with theories holding that top down predictions modulate the response of primary sensory regions to incoming sensory information.
In fact, miRNAs have been shown to modulate the radiosensitivity of primary human dermal microvascular endothelial cells (Wagner-Ecker et al, 2010), lung cancer cells (Weidhaas et al, 2007) and breast cancer cells (Kato et al, 2009).
In those systems, ATP is either a co-transmitter or serves to modulate the effectiveness of the primary transmitter, which is usually glutamate.
The anharmonic modes of motion reveal the exquisite ability of ubiquitin to modulate both the primary and secondary binding surfaces (β1−β2 and β3−β4; β4−α2), as shown in Figure 2. In addition, the distances between β1−β2 and β3−β4 can also serve as order parameters to describe the anharmonic landscape spanned by our simulations.
In the present study, we hypothesized that externally administered HS can modulate the inflammatory reaction, and the primary purpose of this study was to examine the anti-inflammatory effects of HS in a sepsis model.
