Sentence examples for modulate the folding from inspiring English sources

In this article, we discuss how the size, number, and structure of glycans, as well as the attachment sites, may modulate the folding of glycoproteins.

Molecular chaperones are proteins which can modulate the folding of a variety of other polypeptides without permanent alteration to themselves [3].

It may also more directly influence mRNA metabolism and/or translation through its ability to modulate the folding of mRNA [48] and to stabilize mRNA via its binding to AU-rich sequences [49].

As we have seen above, π-π interactions in p63 and in all its variants seem to modulate the folding patterns.

Ribosomes are molecular machines that function in polyribosome complexes to translate genetic information, guide the synthesis of polypeptides, and modulate the folding of nascent proteins.

At the same time, at the N-terminus, a hydrophobic cluster comprising of residues F19, L22, F25 and L26 was observed to form and modulate the folding patterns.

In addition to ubiquitinating clients for targeting to the proteasome (6– 8), CHIP may regulate protein triage decisions by modulating the folding and degradation functions of Hsp90 via HDAC6.

GSTK1 may promote further cross-talk between metabolic signaling and biochemical pathways by modulating the folding and assembly of oligomeric proteins directly involved in lipid synthesis and/or catabolism, including the trimeric DCI protein.

It remains controversial whether the chaperonin system functions solely as an infinite dilution chamber, preventing off-pathway aggregation, or actively enhances folding kinetics by modulating the folding energy landscape.

While work remains to be done, cruentaren A represents a new class of Hsp90 modulators that targets the Hsp90α-F1F0 Hsp90α-F1F0e interATPion and represynthasenew paradinteractionland the Hsp90 prepresentsding machinewy.

'Rescue' of mis-folded and mis-localized membrane proteins is of growing clinical importance [ 6, 34, 35] and has been achieved in vitro with either chemical chaperones (small molecules which modulate either the folding of the protein or the ER recognition of mis-folded proteins) or by reducing the rate of protein translation by lowering the cell culture temperature.