Sentence examples for modulate the proliferative from inspiring English sources

Although more work is needed to establish the exact mechanism of this effect, our results suggest that activation of the tethered ligand thrombin receptor may modulate the proliferative responses of CD34+ hematopoietic progenitor cells.

In contrast, administration of rAAV sox9 did not modulate the proliferative processes in the samples over time versus control treatments in any of the systems evaluated (even though mechanical stimulation led to increased activities), again consistent with the known activities of SOX9 (Akiyama et al. 2004) and with our findings in isolated human bone marrow-derived MSCs (Venkatesan et al. 2012).

Many of these encode transcription factors or cell cycle regulators that directly modulate the proliferative activity of HSC.

We therefore tested whether providing MECs with basement membrane proteins in the form of 3D-matrix might modulate the proliferative potential of MECs.

Cell senescence and stress modulate the proliferative potential of mammalian cells, suggesting that both are capable of suppressing the formation of tumors [ 1- 7].

These results suggest that Hh signaling can modulate the proliferative and invasive phenotypes of GBC cells and that Smo inhibition ameliorates the phenotype.

We next examined whether rAAV-mediated TGF-β and sox9 co-overexpression was capable of modulating the proliferative, metabolic, and differentiation activities in human bone marrow aspirates maintained over time under chondrogenic stimulation relative to control conditions (rAAV-lacZ, no vector treatment).

Therefore, Socs3a is involved in modulating the proliferative role of Trpm7 in exocrine pancreatic epithelia.

However, MVA85A vaccination modulated the proliferative capacity of Ag85A-specific CD4+ T cells, which was markedly higher 6 12 months after MVA85A vaccination, than before vaccination.

This study reveals a mechanism that modulates the proliferative role of Trpm7 in exocrine pancreas by the Mg2+-sensitive Socs3a pathway.

While the aforementioned studies have increased our understanding of flavonoid- and nutrition-based inhibition of oral cancer proliferation, none to date have adequately investigated the role of PAC in modulating the proliferative phenotype of OSCC.