Sentence examples for modified gene expression from inspiring English sources

In particular, emerging evidences suggest that epigenetic alterations, i.e., modified gene expression via DNA methylation, histone modification, or microRNA, of WNT signaling represents an important area of investigation.

Changes in the level of aeration during the cells growth phase significantly modified gene expression profiles and metabolic fluxes in this system.

Furthermore, a study reported that low folate may induce malignant transformation, declining SAM biosynthesis, de novo thymidine monophosphate synthesis, modified gene expression by defective cytosine methylation, or lead to the development of catastrophic cycles of aberrant DNA repair and subsequently uracil misincorporation (Ciappio and Mason 2010).

It remains unclear how epigenetic modifications fix the effects of early environmental events, in a sex-specific manner, ensuring sustained responses to transient stimuli and resulting in modified gene expression patterns and phenotypes later in life [68].

The TALE-LSD1 fusion altered the chromatin at enhancers and modified gene expression.

The modified gene expression of these cells accumulates in the secretion of particular cytokines and presentation of BCG antigens.

These data show that NKX2-5∆HD indirect binding to off-targets can modify gene expression, at least when over-expressed.

HDACs also interact with other epigenetic modifiers such as DNA binding proteins and methyl-binding proteins to further modify gene expression.

The same mediators used for modifying gene expression are used as biomarkers to identify a cell as epithelial or mesenchymal.

Clear evidence exists that AgNano can modify gene expression in animal models both in vivo and in vitro[2 5].

In recent years, various studies have focused on the epigenetic mechanisms that regulate chromatin architecture, thereby modifying gene expression.