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It can have major genetic and genomic effects, such as altering chromosome segregation, masking deleterious mutations, influencing levels of genetic diversity, changing gene expression, causing rearrangements, gene loss and epigenetic changes, rewiring genetic networks, and altering rates of adaptation (Levin 2002; Adams and Wendel 2005; Chen 2007; De Smet and Van de Peer 2012; Madlung 2013).
Imaging rapidly changing gene expression during embryogenesis is a challenge for the development of probes and imaging techniques.
When calories are restricted, the sirtuins become more active, changing gene expression and metabolic pathways, thus increasing the health and lifespan of the organism.
Although the first epigenetic change described in cancer was gene hypomethylation [Holliday R, Jeggo PA: Mechanisms for changing gene expression and their possible relationship to carcinogenesis.
The mechanism for this is beginning to be understood, and it's not entirely shocking, because many pesticides have been shown to be endocrine disruptors, changing gene expression patterns and causing unforeseen harm to health.
Progression of this cancer is associated with the changing gene expression profile.
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These results suggest transcription factor AtOFP8 could change epicuticular waxes content and composition, perhaps by changing genes expression.
During osteoarthritis (OA -development extracellular matrix (ECM) mOA -developmentst from cartilagextracellularing gene-expression, matrix synthECMs and biomoleculesl competence of the tissue.
Two trans-tissue gene lists are defined, the most changing and the least changing genes in expression rank.
Further, CNVs encompassing genes or regulatory elements are believed to exert potentially larger effects on gene expression through changing gene structure and dosage, altering gene regulation, exposing recessive alleles and other mechanisms [ 1, 4, 15, 16].
Genes in the Harries et al. age expression changing gene set30.
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