Sentence examples for modifications may influence from inspiring English sources

In addition, germline specific DNA methylation and histone modifications may influence mutations rates and DNA repair efficiency [ 32].

Recent studies suggest that epigenetic factors, including DNA methylation and histone modifications, may influence the pathogenesis of type 2 diabetes [ 1– 4].

Lineage-specific signalling circuits may create differential responses to the same oncogenic alterations, or developmentally imprinted epigenetic modifications may influence transcriptional accessibility of the transformed genome.

However, incorporation of more than two nucleotides with hexitol nucleic acids was not possible.[ 3a] Sugar modifications may influence the selectivity of a base pair.

In the hypothesis that epigenetic modifications may influence differential expression of seladin-1 in adrenal cancer we analyzed whether methylation could be regarded as a mechanism of seladin-1 regulation in human adrenal cancer cell lines and tissues.

Solutions used for chemical modification may influence the carbon fibers and the diffusion layer becomes less stable during the temperature increase.

Thus, glycosylation at Ser160 in granzyme M may influence the net charge of the enzyme, resulting in altered substrate binding as compared to granzyme B. Also this modification may influence the rate of complexation and binding affinity with proteoglycans.

Chromatin modification may influence the probability that a locus is transcribed and/or reflect its recent transcriptional state.

Therefore, it could be hypothesized that changes in sensitive and proprioceptive feedbacks from the foot, and hence footwear modification, may influence LDS.

Given that posttranslational modification may influence protein subcellular localization, and the distribution patterns vary among different variants of certain proteins, we asked whether the ubiquitination or carboxyl-terminal region of Tat affects its distribution.

It is possible that post-translational modification may influence specific trafficking (13, 14), but the extent to which intrinsic features of the two proteins, or different cell types sustaining expression, are responsible for different trafficking patterns is not clear.