Indeed, dose adjustment may influence the long-term tolerability of pirfenidone.
Sleep disturbances and circadian adjustment may influence either depression or general wellness and vice versa.
Most randomized controlled trials are, however, not large 8 and when the presence of an effect is tenuous (for example, when the results hover around the "attractive" P value of 0.05), 9 decisions regarding adjustment may influence the interpretation of the study outcome.
There is also the possibility of over-adjustment, which may influence the precision of the results.
This result was highly robust and remained after adjustments for factors that may influence outcome.
In their study, Reese et al suggested that relationships may influence adjustment to chronic pain conditions such as RA [ 9].
In cancer survivors, this normal process of ageing may influence adjustment to cancer and treatment over time.
It is known that illumination may influence circadian adjustment, and conversely, circadian adjustment (especially the time of arising) may influence a person's exposure to daylight.
However, risk factors may already be present before the loss occurs and may influence psychological adjustment after the loss.
Analysing determinants of BF and PTG may help to better understand these constructs and the factors that may influence the adjustment of cancer survivors to their disease.
