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Exact(8)
Alternatively, ADNP might directly target RNA polymerase(s) or basal transcription factors involved in major satellite transcription.
The results in Figure 5 and Figure 6 suggested that AtJmj4 and ELF6 might directly target FT chromatin and repress the transcription activity of FT by reducing the methylation level of H3K4.
Accordingly, CagA might directly target intercellular adhesions by disrupting tight [ 73] and adherence junctions [ 144].
The observations led to a speculation that miRNAs might directly target the pluripotent core factors.
There is also evidence suggesting that AMPK might directly target and inhibit TOR [ 14] and AMPK-silencing (by AMPKα RNAI) does result in increased TOR activity [ 15].
To exclude the possibility that the cAMP inhibitors might directly target the co-cultured T cells rather than tumor cells, tumor cell lines were pretreated with the cAMP inhibitors.
Similar(52)
This suggests that the top miRNAs might not directly target and degrade pluripotent core factors.
We might instead directly target the noncognitive elements of the aversion; for example, the physiological arousal that occurs when one is confronted with a person of different race.
It is possible that Pkc1 might also directly target other elements of the chromatin modification machinery to coordinate efficient chromatin assembly such as occurs with Cdc7-Dbf4 whicancalsolso target CAF-1 (chromassemblyembly factor 1) (Gerard et al., 2006) as well as H3T45.
Regardless of the mechanism, recombination proteins might be directly targeted to stressed forks, or they might travel with unperturbed forks to act once they encounter the obstacle.
Decreased ADAM12-L protein and mRNA levels after transfection of miR-29b/c suggested that these miRNAs might be directly targeting the ADAM12-L 3′UTR.
Related(20)
might specifically target
might directly stimulate
might directly be
might directly induce
might directly inhibit
might directly modulate
might directly detract
might directly create
might directly support
might directly alter
might directly impair
might directly decrease
might directly interact
might directly phosphorylate
might directly promote
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might directly serve
might directly depress
might directly compete
might directly act
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