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Therefore, RBV might directly act on glial cells within CNS.
Target receptors of APC that might directly act on hepatocytes are still unknown.
Thus, we could refute the possible involvement of CYP1A1 and AhR in our experimental system, and the PCB congeners each might directly act on TR.
A possible explanation is that BPA might directly act on TH2 cells to promote cytokine production in adult mice as demonstrated in vitro.
With this organisation the ionised carboxylate might directly act as a ligand on the more deeply sited (zinc) ion or potentially hydrogen bond to water ligands on the metal centres.
Collectively, this data demonstrate that both p63 isoforms can regulate caspase-1 expression and also suggest that p63 might directly act on the caspase-1 promoter regulating its expression at the transcriptional level.
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Therefore, although telomerase might not directly act on the carcinogenetic process it certainly is a promoter [ 30].
We considered the possibility that SLC4A11 might not directly act as a water flow pathway, but could activate or unmask some water movement pathway endogenously found in cells.
It has to be pointed out that production of more H2O2 might also contribute to the cell wall reinforcement or directly act as a microbicidal compound during the pathogen invasion.
Moreover, IL-21 can directly act on B cells.
Third, PERP might directly affect some regulators of apoptotic machinery, such as BAX (mean PONDR FIT score of 0.310) or BCL-2 (mean PONDR FIT score of 0.347), or even directly act on some crucial apoptotic effectors, such as the caspases.
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might directly compete
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