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In other words, the music you are listening to might directly alter the way you perceive the world.
In addition, caffeine might directly alter the vasomotor tone by antagonizing A1, A2A and A2B adenosine receptors on smooth muscle cells of the vessel wall and herewith reduce adenosine-mediated vasodilatation [16], [17] resulting in a decreased myocardial blood flow (MBF) response to exercise stress [18] [20].
TDP-43 overexpression might directly alter splicing or stability of RNA targets as shown by dose-dependent toxicity in mice (63, 76, 77).
To address how transcription-generated force might directly alter DNA structure in vivo, Kouzine et al. [ 33] used a tamoxifen-inducible Cre recombinase to excise a chromatin segment with its torsional stress trapped intact.
This finding was consistent to previous studies that some G protein-coupled receptors (GPCRs) were able to promote actin reorganization and result in cell shape changes and enhanced cell migration [ 13, 29], indicating that GPR39 might directly alter the cytoskeleton to favor the tumor cell invasion and metastasis in ESCC.
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It's also possible that exercise might directly change how the FTO gene works, altering whether it expresses certain proteins or remains quiet.
Nothing in the Medicare legislation before Congress would directly alter the hospital payment system.
Some doctors felt that prayer can directly alter the physical process of healing through God's intervention.
It is very hard for policy makers to use money to directly alter these viewpoints.
These experiments demonstrate that altered Cu levels can directly alter Aβ toxicity in flies.
Although mutations directly alter the genome, the resulting functional change is what drives evolutionary selection.
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