Sentence examples for might directly modulate from inspiring English sources

The LRP1 gene has a role in glutamate signalling and the consequence of a reported mutation in rs11172113 might directly modulate NMDA-dependent calcium currents in vitro.

Previous research in animal models of ALS however supports that serotonin might directly modulate onset and survival in ALS.

First, certain collateral signals might directly modulate p53 activity by changing the conformation of p53 or its association with various coactivators, perhaps leading to the expression of different subsets of p53 target genes.

Thus, Src might directly modulate caspase-3 and -7 activities.

Therefore, we reasoned that AcCoA availability might directly modulate autophagic activity.

Once in the nucleus, these growth factors might directly modulate cellular activities [ 39].

One way in which emotions might be directly modulated is through the use of pharmaceuticals and other biomedical technologies, but, as we shall see, there are also non-biomedical means of directly modulating emotions, and these fall within the scope of Harris' critique.

Therefore one plausible explanation is that production of IL-10 might restore the dysregulated Th1/Th2 balance, or it could directly modulate effector cells, including macrophages and dendritic cells, thus downmodulating inflammatory responses.

Hyal2 does not directly modulate the basal or MSP-induced RON/Stk activity, although it is possible that adaptor proteins might mediate such signaling in other cell types.

Based on this background, we hypothesized that CHEB42A and LLZ are functionally related and that CHEB42A might act by directly modulating LLZ channel functions in a cell-autonomous fashion.

Doyle, M. E. & Egan, J. M. Pharmacological agents that directly modulate insulin secretion.