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To generate CPD1 null mice we took advantage of recent developments in high-throughput insertional mutagenesis of mouse embryonic stem cells (ES cells) to generate knock-out mice.
To better understand the finding of increased variance of log-transformed gene expression levels in the hippocampus within more active mice, we took a closer look at the overall distribution pattern of gene expression levels.
As we performed imaging experiments in awake mice, we took respiration behavior into account while analyzing the IOS readout.
To evaluate Kidins220 expression levels in our mutant mice, we took advantage of antibodies raised against the amino- and carboxy- terminal portions of the protein.
To investigate the craniofacial phenotype of the mice, we took dorsoventral X-ray images of the skulls and measured the length of the nasal bone.
Since the available data of expression profile for mouse gastric tumors are limited to our K19-C2mE and its compound mice, we took different strategy to assess the similarity of gastric tumors between the two species.
Similar(53)
Because we found greater variability in the CD40 expression of pDCs from old mice with lupus than from the other groups of mice, we take into account that technical reasons may have hampered the statistical significance in this comparison (Kruskal-Wallis p = 0.018, Mann-Whitney NZM versus BALB/c = 0.064, NZM versus B6 = 0.023).
For each eQTL position and for each mouse, we took the genotypes with maximal multipoint probability to be the observed eQTL genotype, provided that this exceeded 0.99; if no genotype had probability >0.99, the observed eQTL genotype was treated as missing.
Because of the restricted life span of Bmi1 gene ablated mice [19] we took advantage of the higher incidence and shorter latency of the BXB11 founder line to examine the Bmi1 dependence of adenoma growth in advanced disease.
To investigate which of the Pc orthologs is responsible for PRC1 function in mouse ESCs, we took a quantitative proteomic approach (Vermeulen et al., 2010) to identify proteins that bind specifically to H3K27me3.
To investigate IG20/MADD exon 16 splicing in glioma mouse models, we took advantage of the RCAS/tva system, in which the RCAS avian leukosis virus mediates somatic gene transfer into cells expressing the viral receptor (tva) (Dai and Holland, 2001).
Related(20)
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