To quantify the myofiber atrophy observed in the muscles of the Pitx1 transgenic mice, we measured muscle fiber diameter using minimal Feret's diameter measurement, performed on cross sections stained for laminin (Briguet et al., 2004).
To assess presynaptic excitability in epileptic KA mice, we measured the fibre volley amplitude as a function of stimulation intensity.
To further confirm and quantify the histological amelioration observed in Sgca null:Nfix null mice, we measured other important hallmarks characterizing dystrophic muscles at 8 weeks.
To elucidate potential mechanisms by which the induction of arthritis is suppressed in Nampt+/− mice, we measured the serum levels of the arthritogenic anti-mouse CII auto-antibody, which plays a crucial role in the initiation of CIA7.
To understand whether the phenotypic amelioration was mediated by a delayed regeneration, similarly to what observed for Sgca null:Nfix null mice, we measured central nucleation in tibialis anterior and diaphragm muscles of mdx and mdx:Nfix null mice.
In adult (FAS) mice, we measured phosphorylated cyclic adenosine monophosphate response element of binding protein (pCREB) staining in hippocampal subregions to evaluate a possible mechanism underlying FAS learning deficits.
In gastrocnemius of CK−/− mice we measured a 2.5-fold increase in mRNA level for mitochondrial encoded cytochrome c oxidase (COX -III whiCOX -IIesponds to the Increase in protein content.
To obtain direct evidence for interaction of nano-anatase TiO2 with DNA from the liver of mice, we measured the contents of titanium in purified DNA by ICP-MS (Table 2).
To determine the effect of bacterial DNA on cytokine production in NZB/NZW mice, we measured the serum cytokine levels, cell culture supernatant cytokine levels, and number of cytokine-producing splenocytes in NZB/NZW mice injected with EC DNA, calf thymus DNA, or an immune active oligonucleotide.
Studying mice, we measured 6-folds higher mRNA levels in young males then in old animals (p = 0.0019, Figure 5A).
To test whether the presynaptic release probability is altered in the KO mice, we measured responses to paired-pulse stimulation.
