Consistent with our observations in the WAT of Tg mice, we observed down-regulation of Rip140 and up-regulation of Pgc1a.
When comparing RAGE KO and WT mice, we observed no significant differences regarding alveolar barrier dysfunction.
In 28-week-old Fabry mice we observed significantly decreased Gb3 accumulation.
In PPAR-α /– mice we observed delayed stratum corneum formation between day 18.5 of gestation and birth.
Following transplantation of ARSA-overexpressing precursors into ARSA-deficient mice we observed a significant reduction of sulfatide storage up to a distance of 300 µm from grafted cells.
In control mice, we observed more extensive metastases compared to treated mice.
In all infected mice, we observed dense areas of immune cells, indicative of granulomatous lesions.
Particularly in lungs of HVT-ventilated mice, we observed marked changes in the Ang-Tie2 system.
Indeed, in WT mice we observed a developmental regulation in the NMDA/AMPA ratio at these synapses (Table S1).
In contrast, in mice, we observed a total disappearance of the early striosome-associated WFA-positive clusters by P14.
In three experiments involving 10 mice, we observed a faint, transient abdominal luminescence only in two animals.
