Sentence examples for mediate therapeutic effects from inspiring English sources

When combined with CD4+ T cells, transfer of total (naïve and effector) or effector CD8+ T cells were highly effective, suggesting CD4+ T cells can help mediate therapeutic effects by maintaining function of activated CD8+ T cells.

Both oxygen and sumatriptan are considered to mediate therapeutic effects in CH through their vasoconstrictive action [16 20].

Nonetheless, advances are being made with conventional antibodies, showing that minimal exposure can act centrally to mediate therapeutic effects.

Although other mechanisms mediated by genetic inhibitors may also mediate therapeutic effects [12], [30], we found that the antiviral potency of the analyzed transgenes correlated with their ability to provide such a selective advantage.

In multiple myeloma, blocking of NF-κB activation by proteasome inhibitors such as bortezomib is considered to mediate therapeutic effects of bortezomib.

We conclude that syngeneic fibroblasts cotransfected with IL-2 and IL-12 mediate therapeutic effects against established disease, and are capable of generating immunological memory.

My analysis suggests that downregulation of MAP kinase pathway may mediate therapeutic effect of PTZ in DS.

For instance, transferring human microbiota to germ-free mice has validated the causal role of the microbiome in mediating therapeutic effects of metformin and autoimmune therapy (Forslund et al., 2015; Wu et al., 2017; Routy et al., 2018).

However, the full action mechanism of GM-CSF, and especially whether monocytes mediate its therapeutic effects in vivo, had not been previously elucidated.

These cellular and molecular events appear necessary to mediate the therapeutic effects of fluoxetine and may be generated through the ability for fluoxetine to regulate BDNF levels.

Forslund et al. were the first to report that metformin could increase the abundance of bacteria that produce short chain fatty acids (SCFA), and these could mediate the therapeutic effects of metformin (Forslund et al., 2015).