Sentence examples for mediate antitumor effects from inspiring English sources

Granulocyte-monocyte colony stimulating factor (GM-CSF) has been reported to to mediate antitumor effects through stimulation of various antigen presentation cells.

Granulocyte macrophage colony stimulating factor (GMCSF) can mediate antitumor effects by recruiting natural killer cells and by induction of tumor-specific CD8+ cytotoxic T-lymphocytes.

First, Abs may mediate antitumor effects by antibody-dependent cellular cytotoxicity or complement-dependent cytotoxicity [5], [38].

S. typhimurium were initially shown to mediate antitumor effects through recruitment of the host immune system and by competition with cancer cells for nutrients.

Via expression of T-bet and IFN-γ, Th1 cells indirectly mediate antitumor effects by enhancing CD8+ cytotoxic T-lymphocyte and NK cell function [ 23].

Ceramide generation in response to anthracyclines has been implicated in mediating antitumor effects such as cell death and growth arrest.

This study aimed to elucidate the mechanism by which FTY720 mediates antitumor effects in cholangiocarcinoma (CC) cells.

Hyperacetylation of non-histone proteins, including p53 and Hsp-90, may also have important roles in mediating antitumor effects of HDACi.

The sizeable increase in circulating anti-HER2 Th1 populations in pCR patients in the present study may represent a systemic corollary to such immune-related changes in the tumor microenvironment, and lend further support to evidence that intact immune functionality, in addition to HER2-signaling inhibition, is critical in mediating antitumor effects following T + C treatment [ 28].

Moreover, curcumin-cyclodextrin complex potentiated the gemcitabine-mediated antitumor effects.

The first was improved immune response to tumor cells based on a significant reduction of the IL-12 mediated antitumor effect in a T-cell or NK-cell depleted environment [ 8] and the development of antitumor resistance after the combined treatment modality [ 9].