Sentence examples for may modulate multiple from inspiring English sources

RASSF1A promoter methylation is one of the most common molecular changes in cancer, and may modulate multiple apoptotic and cell cycle checkpoint pathways [27].

Preliminary animal data suggest that alteration of the bile acids pool can induce profound alterations in bile acid synthesis, which in turn may modulate multiple metabolic processes.

NOX2 and NOX4 are the main isoforms in the cardiomyocyte, and their activation may modulate multiple signaling pathways and redox-sensitive proteins (7, 8).

It is now evident that AMPK may modulate multiple physiological and pathophysiological pathways including enhancement of eNOS activity by phosphorylation [ 15– 17].

Thus, it is plausible that oxidative stress may modulate multiple mechanisms (e.g., p38 and CRM1) capable of inhibiting ERK oscillations, and the antioxidant status of the cell system may be an additional variable for consideration.

However, siRNA silencing of PKC- α resulted in a less significant apoptotic phenotype in comparison to that observed by miR-203 overexpression, thus suggesting that miR-203 may modulate multiple apoptotic genes that work together to regulate cell apoptosis [ 61].

This implies that standard tES may concurrently modulate multiple cortical, as well as subcortical, neural networks.

Our observations suggest that rational combinations of targeted therapy, which modulate multiple relevant pathways, may be useful in overcoming resistance in patients with Ewing's sarcoma.

miRNAs can also modulate multiple genes regulating entire networks.

How C7ORF41 may modulate TPA-induced multiple signaling pathways remain unclear.

This raises the possibility that theta phase may modulate gamma amplitude in multiple task-relevant regions during cognition (Jensen and Lisman, 1996; for reviews see Lisman and Buzsaki, 2008; Schroeder and Lakatos, 2009; Canolty and Knight, 2010; Jutras and Buffalo, 2010; Fell and Axmacher, 2011).