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Therefore, our study indicates that Snail1 may modulate several steps in RNA maturation, such as polyadenylation and splicing, and so mRNA stability and translation.
Proanthocyanidins have substantial antioxidant activity and may modulate several reactions involved in cancer processes [ 11].
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They modulate several aspects of signal transduction processes [15].
Transglutaminases can modulate several cardiovascular risk factors, especially hypertension [ 3].
FKBPs are multifunctional proteins that modulate several signal transduction pathways.
Several recent neuroimaging studies suggest that meditation may modulate pain through several mechanisms[8].
In conclusion, we have shown that in septic shock patients, hypertonic fluid, compared with isotonic fluid, may modulate expression of several, but not all, measured genes that are implicated in neutrophil-endothelial interaction and capillary leakage.
The rapid and strong detachment of tumor cells exposed to HAMLET might thus reflect the combined activation of ion channels, small GTPases and p38 signaling and α-actinin may act by modulating several of these effects.
Albumin may modulate circulating concentrations of several cytokines in a complex interplay with other components of acid-base status, such as SIG or SIDa.
These data indicate that genetic differences in oxidative events may modulate the risk and/or severity of RA, and that several mechanisms may be involved, some even working in opposite directions.
In order to answer the question whether TRD treatment may modulate signalling pathways common in several different tumour types rather than being tumour cell type specific we subjected the above described different cell lines (HT29 (colon), Chang Liver (liver), HT1080 (fibrosarcoma), AsPC-1, BxPC-3 (both pancreas)) to global gene expression analyses using Agilent microarray technology.
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