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In bacteria degradation by ATP-dependent proteases, belonging to the AAA+ superfamily, participates in regulation of many developmental pathways: the heat shock response, starvation adaptation, DNA damage repair, capsular polysaccharide biosynthesis, sporulation and control of bacteriophage development [1] [5].
The bHLH transcription factors regulate tissue-specific transcription and regulate many developmental pathways [ 1].
As the above examples demonstrate, many developmental pathways include alternative isoforms of key genes.
TF bHLH is regulatory component involved in many developmental pathways as well as in plants metabolism [ 66].
The consequences of robustness, canalisation and capacitance can be very obvious in many developmental pathways due to their effect on morphology.
We therefore believe this system has broad applicability to analyses and dissection of enhancer activity in many developmental pathways and provides an attractive alternative to current transgenic mouse based methods.
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Like many developmental signalling pathways, the Notch pathway has been linked to the aetiology of several different human cancers.
Many developmental signaling pathways, including Notch, Wnt and JNK, require acidified organelles for proper signaling.
Many developmental gene pathways have been found to occur or be activated during regenerative processes [ 22, 23].
Many developmental regulation pathways, such as those involving Wnt [ 38], bone morphogenetic protein(BMP) [ 39], sonic hedgehog [ 39], planar cell polarity (PCP) [ 40], and eph-ephrin [ 41], were also identified in these cells.
Our findings suggest that there are many more developmental pathways that may also need different treatment approaches.
Related(20)
multiple developmental pathways
many developmental stages
many evolutionary pathways
diverse developmental pathways
several developmental pathways
many developmental processes
many developmental checkpoints
many developmental studies
many indirect pathways
many molecular pathways
many cellular pathways
many developmental systems
many interleukin pathways
many developmental genes
many biological pathways
many developmental diseases
many nuclear pathways
many developmental milestones
many developmental enhancers
many such pathways
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