Exact(8)
These results suggest that complex genetic interactions among several developmental pathways are affecting DT.
28 Evidence implies that aberrant activation of several developmental pathways is involved in the formation of CSCs.
Dishevelled (Dsh or Dvl) is an important signaling protein, playing a key role in Wnt signaling and relaying cellular information for several developmental pathways.
The patterning and morphogenesis of body appendages – such as limbs and fins – is orchestrated by the activities of several developmental pathways.
In plants, microRNAs (miRNAs) act as key regulators of several developmental pathways as well as of other molecular mechanisms, such as response to stress, or to environmental changes [ 1, 2].
Several developmental pathways are affected in FASD, including nervous system development, growth and remodeling of tissues, as well as metabolic pathways that regulate glucocorticoid signaling and balanced levels of retinol, insulin and nitric oxide.
Similar(52)
The obtained data is projected on a model of our current knowledge of several developmental signaling pathways.
Thus, OCRL1 is likely to regulate multiple trafficking routes that in turn influence several developmental signalling pathways.
Within KEGG, the acRPB1 enriched genes had nominally significant overlap (uncorrected p < 0.05) with genes involved in several developmental signaling pathways, focal adhesion, and actin cytoskeleton regulation (Additional file 5).
In summary, we present a rigorous analysis of the genomics of the Drosophila group B transcription factor Dichaete, highlighting regulatory input into several key developmental pathways.
Accumulating evidence indicates that hypoactive GSK3β signaling, which functions in G1 to receive input from several signaling and developmental pathways, occurs in association with diverse human cancers [ 21, 22].
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