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Interventions to maintain bleb function will be documented.
Although the use of prior antimetabolite does not affect preservation of bleb function, measures such as 5-FU injection after PPV are believed to maintain bleb function.
Thompson et al. reported that it is difficult to maintain bleb function when 20G conventional PPV is performed after trabeculectomy [ 4].
No treatment that is indicated to maintain bleb function will be withheld (Laser suturolysis, removal of sutures, use of tissue plasminogen activator etc).. Patients will be followed up weekly for 4 weeks until conjunctival sutures are removed.
Although several studies have evaluated the effect of cataract extraction on functioning filtering bleb trabeculectomy outcome, only a few have focused on the impact of PPV on filtering bleb function [ 3]. Thompson et al. reported that it is difficult to maintain bleb function when 20-gauge (20G) conventional vitrectomy is performed after trabeculectomy [ 4].
Similar(55)
Among patients who received trabeculectomy for lowering IOP at Chosun University Hospital from January 2008 to April 2014 and who maintained filtering bleb function, 11 eyes with ≥ 6 months follow-up after 23G PPV for vitreoretinal disease were retrospectively analyzed based on medical records.
The inter-study differences probably resulted from relatively more hypotonic eyes with persistent retinal detachments after vitrectomy reported by Thompson et al. [ 4]. Thompson et al. reported that bleb function was only maintained in 1/3 of cases where vitrectomy was performed after trabeculectomy [ 4].
To determine the efficacy of a subconjunctival injection of hyaluronic acid (HA) with 5-fluorouracil (5FU) formulation as an adjunct in reviving bleb function by needling.
Sutures removal and bleb needling to improve bleb function were not considered failure of the procedure.
Conjunctival edema that occurs during surgery negatively affects bleb function by invading the bleb margin; however, we found no differences in IOP before and after the surgery.
23G PPV did not adversely affect bleb function in eyes with prior trabeculectomy.
Related(20)
maintain neurological function
maintain proper function
maintain certain function
maintain hepatocellular function
maintain hepatocyte function
maintain optimal function
maintain physical function
maintain desirable function
maintain mental function
maintain cellular function
maintain mitochondrial function
maintain adequate function
maintain high function
maintain normal function
maintain hepatic function
maintain cardiac function
maintain renal function
maintain correct function
maintain cognitive function
maintain cardiorespiratory function
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