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Giordano, F.J. et al. A cardiac myocyte vascular endothelial growth factor paracrine pathway is required to maintain cardiac function.
For successful treatment of myocardial infarction (MI), it is important to prevent cardiac fibrosis and maintain cardiac function by protecting cardiomyocytes and inducing angiogenesis.
Although, early remodeling is an adaptive response to maintain cardiac function, it progressively becomes maladaptive and results in the progression of cardiovascular diseases.
To maintain cardiac function at low temperatures, it is possible that white sharks possess adaptations similar to those found in the closely related salmon sharks (Lamna ditropis).
While it is likely that body-core temperature remains substantially elevated above water temperature during the dives, the question that remains is how the sharks are able to maintain cardiac function and support aerobic metabolism at low temperatures.
The salmon shark's ability to maintain cardiac function in cold water has been linked to the up-regulation of proteins required for excitation-contraction coupling and consequently, maintaining heart rate [54].
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Kohsaka, A. et al. The circadian clock maintains cardiac function by regulating mitochondrial metabolism in mice.
Cardiac remodeling, whether through anabolic or catabolic processes, initially improves or maintains cardiac function.
To treat hypothermia in patients with a maintained cardiac function, a "low stress strategy" is first recommended.
Coronary blood flow is important for maintaining cardiac function, and neovascular formation is necessary to compensate for the increased oxygen demand of hypertrophic heart as well as developmental heart1.
These findings suggest that therapeutic inhibition of MK2 after acute MI, using rationally-designed cell-permeant peptides, inhibits cardiac fibrosis and maintains cardiac function by mechanisms that involve inhibiting cardiomyocyte apoptosis, while enhancing primary cardiac fibroblast cell death.
More suggestions(15)
preserving cardiac function
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maintain cardiac chamber
maintain visual function
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maintain bleb function
maintain cardiac homeostasis
maintain cardiac inflammation
maintain phenotypic function
maintain cardiac scope
maintain mental function
maintain cardiac preload
maintain mitochondrial function
maintain cardiac output
maintain cardiac hypertrophy
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