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We also demonstrate that Blm10 acts to maintain mitochondrial function.
These processes serve to maintain mitochondrial function and ensure optimal energy supply for the cell.
These data demonstrate that tumour elicited c-Kit signalling drives both the increase in neutrophil number and mitochondrial fitness resulting in an oxidative population of neutrophils which use fatty acid metabolism to maintain mitochondrial function.
In this context, autophagy is essential for synthesis of minimal essential proteins to maintain mitochondrial function during nitrogen starvation.
Regulation of autophagy and especially the autophagic degradation of mitochondria is an essential tool to maintain mitochondrial function and cellular homeostasis.
Similarly, Pnc1p induction in mistranslating cells could prevent cell death and could maintain mitochondrial function by clearing nicotinamide inhibition and promoting NAD recycling and, thus, modulate the activity of other NAD+-dependent histone deacetylases.
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We postulate that long term PRC inhibition by ShRNA could induce compensatory mechanisms to maintain mitochondrial functions used for other cellular metabolisms.
Taken together, these data identify Clu as a mitochondrially-associated protein that plays a direct role in maintaining mitochondrial function and that binds TOM20, and support a role for Clu linking mitochondrial function to the PINK1-Park pathway.
Chen, Y.-C. Y.-C.. Msp1/ATAD1 maintains mitochondrial function by facilitating thetdegralation of Msp1/ATAD1ed tail-anchored proteins.
Conclusion: The results indicate that preterm fetuses are more capable than term fetuses of maintaining mitochondrial function under conditions of transient intrauterine ischemia and suggest that oxygenderived free radicals may play a crucial role in the development of neonatal neurologic deficit.
We examined the critical roles played by the antioxidant, non-protein thiol, glutathione and related enzyme, glutaredoxin in maintaining mitochondrial function during excitotoxicity caused by β-N-oxalyl amino-l-alanine (l-BOAA), the causative factor of neurolathyrism, a motor neuron disease involving the pyramidal system.
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maintain mitochondrial cristae
maintain high function
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maintain cognitive function
maintain cardiorespiratory function
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