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It is known that, because of the slow course of aging, the nervous system can compensate and maintain adequate function even in centenarians.
More durable mitochondria maintain adequate function longer than less durable mitochondria, and this in part determines aging success.
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Maintaining adequate function in expanding adipose tissue is dependent on angiogenesis, and adipose tissue mass can thus be regulated through the vasculature.
The important role of knee menisci to maintain adequate knee function is frequently impaired since early stages of knee joint degeneration.
Elderly healthy individuals have had capacity to maintain adequate ER function.
In this study, the students were able to maintain adequate cardiovascular function while performing physical activities outdoors.
To maintain adequate brain function and neuronal integrity, cerebral blood flow (CBF) under physiologic circumstances is autoregulated within a wide range of cerebral perfusion pressure.
For example, preventing EndMT during chronic organ fibrosis may significantly delay disease progression and allow patients to maintain adequate organ function for a longer period of time.
4 In this context, the distinction between individuals who will maintain adequate cognitive function into their later years and those on a trajectory to dementia is a fundamental question being pursued.
It is intriguing that with advancing age, these animals develop fairly extensive (>50%) MNs loss with minimal symptoms, possibly reflecting the slow evolution of pathology, providing time for compensatory mechanisms to maintain adequate motor function.
In hepatocytes, the mechanisms of sustaining cytosolic redox homoeostasis are enormously robust as a result of having three pathways, two NADPH-dependent and one methionine-dependent, to reduce disulfides, any one of which can alone maintain adequate hepatic function for long-term survival.
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