Sentence examples for maintain hepatic function from inspiring English sources
These results suggested that HB-EGF/heparin-IC is able to effectively maintain hepatic function via continuous signaling of HB-EGF.
In this chapter, we sought to provide a thorough description of the liver ECM and its intrinsic association with the cells that constitute the hepatic tissue, as well as their location (zonation) and associations in order to maintain hepatic function.
Here, we present an overview of isolated primary hepatocytes and stem cell-derived HLCs used for liver regeneration and describe how the in vitro environment in which they are cultured is continuously being optimized to mimic in vivo conditions and maintain hepatic function.
In cases of irreversible liver failure, such as cirrhosis and fulminant hepatic failure, a promising in vitro system to maintain hepatic function is vital.
Inspired by the in vivo situation, researchers set up attempts to maintain hepatic function in vitro by co-culturing hepatocytes with NPCs (Langenbach et al. 1979; Talamini et al. 1998).
Sufficient endogenous availability of nutrients and metabolites such as glutamine, taurine, choline, and probably carnitine can help to maintain hepatic functions.
Persistent inflammation and cell destruction during HCV infection has been suggested to induce proliferation of normally quiescent hepatocytes [ 17- 19], which helps in restoring liver mass and maintaining hepatic function.
The complex 3D interaction involving NPCs and the ECM is believed to be crucial in regulating and maintaining hepatic function in vivo (Koide et al. 1989; Landry et al. 1985; Wu et al. 1999).
For example, the kidney increases filtration as renal perfusion pressure increases because its role is to filter solute from the blood, whereas the liver maintains a relatively constant flow from the combined hepatic artery and portal vein so as to maintain hepatic clearance and metabolic functions.
Dear Editor, Gluconeogenesis is one of the major mechanisms to maintain hepatic glucose homeostasis and dysregulation of hepatic gluconeogenesis contributes to hyperglycemia in type 2 diabetes.
Homeostatic processes strive to maintain hepatic GSH content and maintain a reduced intracellular environment.
