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Thus, by affecting cell cycle, EMT/MET may influence histone modifications and subsequent cell fate conversion.
Thus, ECM1 may positively regulate cell proliferation by affecting cell cycle progression.
Therefore, our results suggested that EAC-B suppressed MGC-803 proliferation by affecting cell cycle arrest and inhibiting Cyclin D1.
MF may inhibit A549 cells and can increase their sensitivity to RT, possibly by affecting cell cycle- and apoptosis-related signaling pathways.
DC-SCRIPT mRNA expression in breast cancer patients negatively correlated with many cell cycle proteins (Table 2), suggesting that DC-SCRIPT expression inhibits cell growth by affecting cell cycle progression.
TanIIA inhibits the growth of esophageal cancer cells and induces apoptosis in a time-dependent and concentration-dependent manner, possibly by affecting cell cycle- and apoptosis-related signaling pathways.
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These results reveal novel mechanisms by which TFII-I and DBC1 can modulate cellular fate by affecting cell-cycle control as well as HR pathway.
In D. melanogaster, ING1 is thought to interact with p53, which is a transcription factor that can respond to stress by affecting cell-cycle arrest, DNA repair, apoptosis, or senescence [ 49].
miR-124 and miR-34, well defined tumor suppressors, are subject to epigenetic silencing by aberrant DNA hypermethylation affecting cell cycle pathways in tumors 54,57,58; while down-regulation of miR-34 affects the Notch pathway involved in cell invasion and apoptosis.
In addition, a visual screen of this deletion resource for mutants affecting cell cycle (detected by effects on cell length) and cell shape has provided broad morphology phenotype annotations for many gene products (representing both viable cells and the terminal phenotypes of nonviable deletions) (Hayles et al. 2013).
We have also demonstrated how these modulators inhibit cell growth, affect cell cycle by blocking G2-M progress and induce apoptotic cell death.
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by facilitating cell cycle
by impacting cell cycle
by altering cell cycle
by influencing cell cycle
by affecting cell fate
by affecting cell migration
by affecting cell cell
by affecting cell size
by affecting cell damage
by affecting cell membrane
by mediating cell cycle
by affecting cell death
by affecting cell growth
by affecting cell wall
by affecting cell surface
by affecting cell division
by affecting cell sensitivity
by affecting cell signalling
by affecting cell expansion
by measuring cell cycle
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