Sentence examples for by altering cell cycle from inspiring English sources

In vitro and in vivo model systems overexpressing PTGS2 have shown that PGE2 can promote tumorigenesis by altering cell cycle progression, inhibiting apoptosis and enhancing cellular proliferation [11], [12], [13].

Flow cytometric analysis was performed to further examine whether the effect of TUG1 on proliferation of NSCLC cells by altering cell cycle progression.

In addition to the potential of growth factor inhibitors to reverse pro-survival signal, they may also sensitize cells to irradiation by altering cell cycle control.

In the present study, we hypothesized that genes expressed by L. intracellularis in the host cytoplasm are capable of inducing proliferation and preventing differentiation of immature enterocytes by altering cell cycle-associated pathways.

To find out whether the effect of PANDAR on proliferation of NSCLC cells was by altering cell-cycle progression or apoptosis, flow cytometric analysis was performed.

Among these genes, PCNA is responsible for the DNA synthesis and CCND1 could alter cell cycle by regulating the CDK kinases [ 51, 52].

The possibility exists that the phosphorylation status of Id2 may alter cell cycle progression by regulating cyclin A expression.

Importantly, we found that HDACi alter cell cycle progression by decreasing the expression of G2 checkpoint kinases Wee1 and checkpoint kinase 1 (Chk1).

Developed resistance is characterized by decreased potency of XPO1 inhibitors, altered cell cycle profile and less forced nuclear retention of XPO1 cargo.

Interestingly, G1, S and G2 cell cycle phases measured by flow cytometric analysis are comparable between control and IGF-1Ea cells, indicating that the signaling cascade mediated by this specific propeptide did not alter cell cycle in this clone (Fig. 2B).

In searching for putative resistance pathways for RT, we, by genomic profiling, identified Ephrin B3 to impede RT-induced cell death and to alter cell cycle regulation.