Sentence examples for by facilitating cell cycle from inspiring English sources
Collectively, our data demonstrates that Akt2 is crucial for cell proliferation and survival by facilitating cell cycle progression, augmenting p70S6K activity, and modulating mitochondrial biogenesis.
Collectively, our data demonstrates that Akt2 augments cell proliferation by facilitating cell cycle progression through the upregulation of the cell cycle engine, and protects a cell from pathological autophagy by modulating mitochondrial homeostasis.
Transfection of a pre-miR-9 precursor significantly silenced CDX2 expression and increased cell growth by facilitating cell cycle progression (Ref. 95).
Furthermore, checkpoint-related proteins are important candidates for such parameters because they enhance apoptosis induced by cytotoxic treatment by facilitating cell cycle arrest [9].
Our result also suggests a new way by which MIF may contribute to tumorigenesis: facilitating cell cycle progression and proliferation through β-arrestin1 mediated sustained ERK activation.
Activated by phosphorylation on serines 317 and 345, Chk1 phosphorylates the Cdc25 phosphatase family members facilitating cell cycle arrest (Liu et al. 2000; Löffler et al. 2006).
Kim, A. M. et al. Zinc sparks are triggered by fertilization and facilitate cell cycle resumption in mammalian eggs.
RASSF1A primarily interacts with small GTPases such as Ras to facilitate cell cycle arrest and apoptosis.
Following activation, Chk1 phosphorylates and inactivates Cdc25 phosphatase family members to facilitate cell cycle arrest [ 41].
At later stages, inactivation of the p16 tumor suppressor gene occurs, followed by the loss of TP53, SMAD4, and BRCA2 signaling pathways and the genomic-transcriptomic alterations that facilitate cell cycle deregulation, cell survival, invasion, and metastases [ 4].
We have further demonstrated a novel role for ANXA2 in NSCLC cell proliferation by facilitating the cell cycle through the maintenance of JNK/c-Jun-inhibited p53 [ 65].
