Translation is prevented by mRNA deadenylation, mRNA target cleavage or translational repression [ 11].
miRNAs act to repress expression of their target genes via mRNA cleavage or translational repression.
MicroRNAs (miRNAs) regulate targeted mRNAs through a combination of translational repression and mRNA destabilization.
Collectively, these results indicate that eIF4E2 is required for miRNA-mediated translational repression of endogenous proteins.
They regulate gene expression by triggering sequence-specific cleavage or translational repression of target transcripts.
These include both studies on the regulatory effects of transcription factors and translational repression via microRNAs.
MicroRNAs (miRNAs) are negative regulators of gene expression via mRNA degradation or translational repression.
Introduction MicroRNAs (miRs) are noncoding RNAs found in all eukaryotic cells that regulate the human genome, primarily through translational repression.
MiRNAs can suppress the expression of target genes through translational repression or through degradation of a target's transcript.
We next used the polysome profiling assay to confirm that eIF4E2 participates in miRNA mediated translational repression.
Transcripts of a subset of SPLs are targeted for cleavage and/or translational repression by microRNA156s (microRNA156s
