Sentence examples for surrogate cell from inspiring English sources

The key aim of the current study was therefore to establish a suitable surrogate cell system, free from the influence of post mortem artefact, in which to investigate dynamic functional investigations of disease-associated pathophysiological mechanisms as well as the identification of schizophrenia biomarkers, whilst limiting problems such as drug effects.

We found mature IL-1β secreted by macrophages or in our surrogate cell system to be completely soluble, thus inconsistent with the engulfment model (data not shown).

In surrogate cell types, the GR binding affinity and GR-mediated transactivation potencies for DEX, FA, or TA in are similar (1 - 5 nM), and represent the aggregate affinity or transactivation potency generated by multiple GRα and GRβ isoforms.

For example, MAP invasion into Madin-Darby Bovine Kidney (MDBK) cells, another surrogate cell type for the intestinal epithelium, upregulated an oxidoreductase (MAP3464) to regulate the Cdc42 pathway [ 25].

For determination of the cell number (using DNA concentration as surrogate), cell layers were washed with PBS and frozen with 1 mM TRIS-HCl buffer (pH 8.0) containing 0.1 mM EDTA.

Using surrogate cell lines rather than macrophages to reconstitute autophagy-mediated secretion of IL-1β, we find mature IL-1β localized to the lumen of the membrane in early intermediates and mature autophagosomes.

We provide a new approach using short-activating RNA in developing insulin producing surrogate cells for treating diabetes.

Cylindrical 18650-type surrogate cells were designed and fabricated to mimic the thermophysical properties and behavior of active lithium-ion batteries.

Further work on buccal cells and other possible surrogate cells will be a fruitful area.

We proved the concept that AZD3409 can inhibit FTase activity in surrogate cells, that is, PBMCs.

Alternatively, one may look for and use valid surrogate tissues or surrogate cells of the true effects compartments.