Sentence examples for mutations were transmitted from inspiring English sources

In mice, in fact, mutations were transmitted transgenerationally (i.e. they were attributed to DNA damage in sperm cells).

The LgDel mutation (heterozygous deletion on mmchr. 16 from Idd to Hira) and Tbx1 mutations were transmitted paternally; Raldh2+/− was transmitted maternally.

To determine the reason why p5cr mutations were transmitted through the male germline, while p5cs1/p5cs2 double mutations were not, pollen grains collected from open flowers of p5cs and p5cr mutant plants were stained with Alexander stain.

For the most active TALEN pairs, namely those targeting ADH1 and NATA2, we found that TALEN-induced mutations were transmitted to the next generation at frequencies of 1.5 12%.

We determined the biallelic mutations for both TRY and CPC based on their clustered trichome phenotypes, finding that the TRY and CPC mutations were transmitted to T2 plants with high efficiency; 46.2%, 100%, 82.6%, 100%, and 100% of nontransgenic T2 plants derived from five T1 lines, respectively, were biallelic mutants for both TRY and CPC (Table  1).

In addition, these mutations are transmitted through the germline with sufficiently high frequency such that only a small number of fish need to be screened to identify founders.

The mutation probably happens in the female germ line or in embryonic development but there is a mystery: few mutations are transmitted to each successive generation.

Because this protocol induces mutations in germ-line stem cells, mutations are transmitted at the rate for at least several months after the treatment.

In addition, the mitochondrial genome being maternally inherited and not subjected to recombination, mtDNA mutations are transmitted clonally across generations and can be used to trace maternal lineages.

Many mtDNA mutations are transmitted down the maternal line and cause progressive, disabling multi-system disease, often with devastating effects on the nervous system.

Unless multiple affected patients are reported with the same mutation, the mutations are transmitted through pedigrees, and functional assays verify their effects, these variants in patients are generally be classified as VUS.