Sentence examples for mutations were analyzed from inspiring English sources
Therefore, these residues were then substituted with alanine in full-length β4 subunit (except that Asp166 was mutated into Arg166), and the effects on BK channel gating characteristics by these mutations were analyzed after co-expression of these β4 mutants with mSlo1 subunit.
Potential driver mutations were analyzed to determine common driver mutations for each patient (Supplementary Table 4).
Higher-order interactions among identified mutations were analyzed by co-variation and cluster analyses.
Possible functional consequences of the mutations were analyzed using protein modeling and structural mobility analyses.
Structural changes resulting from the mutations were analyzed and the mechanisms responsible for the enhanced activity were discussed.
K-ras mutations were analyzed by 2-step polymerase chain reaction and restriction fragment length polymorphism, APC mutations by in vitro-synthesized protein assay, and β-catenin mutations by direct sequencing.
When each cluster of mutations was analyzed as an independent genome, NNMF reported striking differences in prevalence of specific mutational signatures between clonal and subclonal events (Fig. 6a c and Supplementary Figure 8).
The presence of mutations was analyzed for an association with hematologic phenotypes, survival, and cardiovascular events.Detectable somatic mutations were rare in persons younger than 40 years of age but rose appreciably in frequency with age.
All non-synonymous mutations are analyzed, using Uniprot identifier O95835 for LATS1 and Q9NRM7 for LATS2.
The appearance of Gag mutations was analyzed overall and within subsets of minor, transient, dominant, and complete mutations.
The evolutionary conservation of amino acid sites with mutations was analyzed using ConSurf[25], [51], [52], based on alignments shown in Fig. S2 and S3.
