Non-codon 600 mutations were observed in 37 % of BRAF-mutated tumors.
A mean of 46 (range 3 146) significant somatic mutations were observed per patient.
No recurrent somatic mutations were observed in pediatric nodal marginal zone lymphoma.
The TCRBV09-01 clone, in which mutations were observed, increased slightly during the follow-up.
Overall, urothelial carcinoma specific mtDNA mutations were observed in 20 of the 26 patients (76.9%).
Lower incidences of NOTCH1 mutations were observed compared with that described in metastatic head and neck cutaneous squamous cell carcinoma in the literature.
In pediatric marginal zone lymphoma, no recurrent mutation was identified; however, somatic point mutations were observed in genes involved in cellular adhesion, cytokine regulatory elements, and cellular proliferation.
A total of eight independent mutations were observed in the proline transporter protein BCAL1252, seven of which were in P1L isolate.
MMAC1 coding-region mutations were observed in a number of glioma, prostate, kidney and breast carcinoma cell lines or tumour specimens.
Fifty-nine nucleotide mutations were observed in P1 genes of type I isolates (51 in RepMP4, 8 in RepMP2/3).
No mutations were observed in closely related AHR genes (AHR1a, AHR1b, AHR2a, AHRR) in the CRISPR-Cas9-injected embryos.
